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Chronic pain management for major burn patients may pose a challenge for even the most experienced clinician as there is a constant struggle between creation of opioid treatment plans and the development of opioid tolerance due to this chronic therapy. Dr. P. Desocio and his co-workers at Fort Sam Houston (USA) have therefore designed a study to perform ultra rapid opioid detoxification (UROD) in severely burned service members using dexmedetomidine, ketamine and naloxone to reduce narcotic requirements of these patients by fifty percent. [more...]
 

"Predictive autoantibodies will have multiple uses in the future years. They may be valuable adjuncts in predicting the likelihood of developing clinical disease before the diagnostic signs are evident. They will have value in teaching us about the natural history of disease, particularly in providing information about the length of the prodromal period when the immune-mediated destructive process is silently underway", Noel R. Rose (Johns Hopkins University Baltimore) notes. [more...]
 

January 28, 2010

Movement comes with appetite
A body that is provided with food too often gets caught up in the maelstrom of a lack of exercise, obesity and ultimately diabetes. The trigger is a molecular switch that is controlled by insulin, a new study by scientists from ETH Zurich has revealed. [more...]
 

Anticoagulation therapy for thromboembolism prophylaxis in patients with atrial fibrillation (AF) still is a conundrum for many physicians. Age is the most cited argument to withhold anticoagulation, however, because of their higher risk of stroke, elderly patients would have a greater net benefit of antithrombotic therapy compared to younger patients. Dr. Leithäuser, Dr. Park (both Asklepios Clinik Harburg, Germany) and Dr. Jung (Center for Biomaterial Development and Berlin Brandenburg Center for Regnerative Therapies, Teltow, Germany) carried out a detailed and comprehensive review of the risks of cardioembolic stroke and bleeding in patients with AF with and without oral anticoagulation to clarify anticoagulation underuse in the elderly. [more...]
 

Atrial fibrillation, one of the most common arrhythmias, is responsible for a high percentage of strokes. Efficacy of epicardial microwave (MW) ablation was investigated by a research group at the Heart Center Dresden (Dr. Knaut, Dr. Brose, Dr. Forker and Dr. Matschke) and Prof. Dr. Jung (Center for Biomaterial Development and Berlin Brandenburg Center for Regnerative Therapies, Teltow, Germany) and they recently presented their first clinical results of epicardial MW ablation as a concomitant procedure during cardiac surgery where opening of the left atrium was not required. [more...]
 

Studies of the circle of Willis based on magnetic resonance angiography have revealed a huge amount of variants where certain connecting vessels are missing or hypo-plastic. State-of-the-art techniques have to be used to provide proper assessment of an individual’s vascular tree anatomy and function. Dr. Günther (mediri GmbH, Heidelberg and University Hospital Mannheim, Germany) has summarized recent developments in non-invasive measurement of macro-vascular blood flow and micro-vascular perfusion and has published some results on cerebral vasculature imaging in Applied Cardiopulmonary Pathophysiology 13 (issue 3-2009). [more...]
 

Relevance of increased pulmonary resistance due to higher density and viscosity of xenon/oxygen mixtures in comparison to nitrogen/oxygen has been investigated in an animal study at the University of Ulm, Germany. Dr. Schmidt, Dr. Marx, Dr. Papp-Jambor, Dr. Reinelt (University Hospital Ulm) and Prof. Dr. Schirmer (German Heart Center, Bad-Oeynhausen, Germany) have randomly assigned 14 pigs (German Landrace) to receive either 75% xenon in oxygen (75 animals) or 75% nitrogen in oxygen mixtures (25 animals) under condition of normo-, hypo- and hyperventilation. [more...]
 

"Bioterrorism is a tangible and very dangerous threat worldwide. Intensive efforts should be made to prevent or foil it and to create a suitable medical response should prevention fail", Dr. Meir Oren (Haifa/Israel) emphasizes. [more...]
 

Does helping behavior determine moral development? Various theories predict such a causal relationship. In his study Dr. Georg Lind wanted to answer the question: "Does the participation in an institution with high prosocial aims and value - either through internalization, or through sozial pressure, or through role-taking opportunities - increase the moral development of its members?" [more...]
 

Women are more likely than men to die as a result of mercy killing by family members, while men, particularly husbands, are more likely to be in the role of the mercy killer, Silvia Sara Canetto (Colorado State University/USA) reports. [more...]
 

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Chronobiology and Chronopsychology, by Baudson, T.G., Seemüller, A., Dresler, M. (Eds.)





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