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This is Dr. Brann and Dr. Zhang (GRU Photographer) |
Women who abruptly and prematurely lose estrogen from surgical menopause have a two-fold increase in cognitive decline and dementia. "This is what the clinical studies indicate and our animal studies looking at the underlying mechanisms back this up," said Brann, corresponding author of the study in the journal Brain. "We wanted to find out why that is occurring. We suspect it's due to the premature loss of estrogen." [more...]
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Women's abilities to make fair decisions when competing interests are at stake make them better corporate leaders, researchers have found. A survey of more than 600 board directors showed that women are more likely to consider the rights of others and to take a cooperative approach to decision-making. This approach translates into better performance for their companies. [more...]
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© freshidea - Fotolia.com |
Viewed from the outside, our body looks completely symmetrical. However, most internal organs – including the heart – are formed asymmetrically. The right side of the heart is responsible for pulmonary circulation; the left side supplies the rest of the body. This asymmetry allows the heart to do its job effectively. In a study on zebrafish embryos, the MDC researchers Dr. Justus Veerkamp and PD Dr. Salim Seyfried have now shown how the left and right sides of the heart develop differently. Their findings were published in the journal Developmental Cell (doi: dx.doi.org/10.1016/j.devcel.2013.01.026)*. [more...]
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"The reasons for an incongruity with regard to marital relationship quality between individuals with dementia and their partners are mostly explained as being linked to caregiving stress and a feeling of having lost a coequal partner in the healthy spouse and denial on the side of the afflicted partner," Milena von Kutzleben and Wolfgang Schmid report (in their contribution to the new booklet "Dementia Care Research"). [more...]
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There are risks in testing new medicines - regardeless of the age of the clinical-trial-participant. How can we improve paediatric clinical trials? John E. Chaplin (Goeteborg/Sweden) and colleagues give answers (in their new textbook "Respect - patient needs"): Priority must be given to the empowerment of children as a way forward to improving paediatric clinical trial practice. [more...]
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In new research published in the April 4, 2013 issue of The American Journal of Human Genetics, researchers from Brigham and Women's Hospital (BWH) demonstrate that some variants in our genes that could put a person at risk for inflammatory diseases such as multiple sclerosis, Crohn's disease or rheumatoid arthritis, have been the target of natural selection over the course of human history. The research team, led by Philip De Jager, MD, PhD, BWH Department of Neurology, and Barbara Stranger, PhD, University of Chicago looked at genome-wide association studies along with protein-protein interaction networks, as well as other data and found 21 places in the genome that bear a 'signature' for both inflammatory disease susceptibility and natural selection. [more...]
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By charting the differing fates of individual T cells, researchers have shown that previously unpredictable aspects of the adaptive immune response can be effectively modeled. The crucial question: What determines which of the immune system's millions of cells will mobilize to fight an acute infection and which will be held back to survive long-term, forming the basis of the immunological memory? The scientists' findings, published in the journal Science, could have implications for improved immunotherapy and vaccination strategies. [more...]
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After outgrowing teenage infatuations with the girl next door, adult males seem to be biologically designed to avoid amorous attractions to the wife next door, according to a University of Missouri study that found adult males’ testosterone levels dropped when they were interacting with the marital partner of a close friend. Understanding the biological mechanisms that keep men from constantly competing for each others’ wives may shed light on how people manage to cooperate on the levels of neighborhoods, cities and even globally. [more...]
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© Sven Hoppe - Fotolia.com |
Among individuals with chronic kidney disease, adherence to a healthy lifestyle was associated with a greater likelihood of surviving over a 13-year period.
The greatest survival benefits were related to nonsmoking.
60 million people globally have chronic kidney disease. [more...]
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© arsdigital - Fotolia.com |
In an analysis of 695 patients with kidney failure, Blacks had received less transplant education, were less knowledgeable about transplantation, and were less willing to pursue deceased or living donor transplantation than Whites.
Patients who began a transplant evaluation process with a greater knowledge of transplantation and greater motivation to receive living donor transplants were ultimately more successful at receiving a living donor transplant.
In 2010, a total of 28,662 kidney transplants took place in the U.S. Of those, only 6,809 were from living donors. [more...]
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