A combined treatment strategy targeting SARS-CoV-2 symptoms and severe lung tissue injury is essential to minimize lung sequelae—chronic complications resulting from COVID-19 infection, according to a review published this week in Clinical Microbiology Reviews, a journal of the American Society for Microbiology.
Therapy using lung epithelial stem and progenitor cells shows promise for mitigating the potentially lethal and highly damaging virus-induced inflammatory storm that can occur in severe cases of COVID-19, said Huaiyong Chen, Ph.D., principal investigator at Tianjin Institute of Respiratory Diseases, and Director of Tianjin Key Laboratory of Lung Regenerative Medicine, Haihe Hospital, Tianjin University, China.