Intracerebral hemorrhage during ECMO is associated with up to 50 percent mortality

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June 23, 2021

Intracerebral hemorrhage is a devastating complication in patients treated with extracorporeal-membrane-oxygenation (ECMO) due to acute respiratory or cardiac issues. Despite its high relevance, neurosurgical evaluation and management has insufficiently been studied and evidence-guided decision making with respect to the type of the intracerebral hemorrhage, coagulation management and surgical intervention is very limited.

Journal für Anästhesie und Intensivbehandlung 2021-1

EXTRACORPOREAL CIRCULATION In Theory and Practice

Facing the rapidly worldwide spreading increase of extracorporeal life support therapy cases surgeons and anesthesiologists (Charite, Berlin) studied the relationship between ECMO associated intracerebral hemorrhage, different bleeding patterns, neurosurgical management and clinical outcome. The results are published in Journal für Anästhesie und Intensivbehandlung 1/2021:

A total of 525 patients with ECMO were eligible for analysis. Of those, 24 (4,6%) patients developed an intracerebral hemorrhage. 11 of the 24 patients died under therapy. Intracerebral hemorrhage during ECMO was independently associated with up to 50 percent in-hospital mortality. This is the first study evaluating the course and management of patients experiencing an intracerebral hemorrhage under ECMO ...

V. Prinz, M. Menk, P. Vajkoczy, T. Finger (2021): Clinical management and outcome of adult patients with extracorporeal life support device associated intracerebral hemorrhage. Journal für Anästhesie und Intensivbehandlung, 1/2021

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