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    Dialysis Therapy: How to diagnose, prevent and treat cardiovascular diseases

    "Cardiac disease is the major cause of death in dialysis patients, acccounting for half of the total mortality. When routinely assessed by echocardiography, the proportion of patients with abnormal dimensions of cardiac compartments is even higher. When chronic kidney disease progresses, cardiovascular damage starts to develop and may already be quite severe before dialysis is started. Initiation of dialysis treatment comes with a step further increase in cardiovascular mortality during the first year of treatment, and remains very high thereafter," Prof. Dr. Branko Braam and colleagues report in the textbook "Hypertension and Cardiovascular Aspects of Dialysis Treatment".

    Hypertension and Cardiovascular Aspects of Dialysis Treatment – Clinical management of volume control

    "Unfortunately some authors suggest that the development is the result of some intrinsic cardiac process, while in reality its course is importantly determined by extrinsic, controllable factors, i.e. the way of treatment. Dialysis provides a unique opportunity to correct some of these disturbances and thus slow down, improve, ore even cure complications, which once were considered inevitable."

    The authors describe detailed: Methods of investigation, prevention and treatment of cardiac dilatation, left ventricular hypertrophy, congestive heart failure, valvular disease, dilated cardiomyopathy, sudden cardiac death and arrhythmias in iremic patients

    Whatever structural alterations in the heart are present, fluid retention plays a contributory and pivotal role. When a normal heart can fail with volume overload, a diseased heart will suffer even more, and good volume control is more urgent than ever. Remarkable improvements in clinic and echocardiographic disturbances can be achieved by judicious ultrafiltration, anginal complaints can be relieved , appetite can improve. When severe dilated cardiomyopathy is present, hypertension disappears and blood pressure may become subnormal, strengthening te conviction that the condition is beyond repair.

    Particularly when gross cardiac dilatation and systolic dysfunction are present, patience and perseverance by the dialysis team are required, because adaption and ´remodeling´ of the stretched heart muscle take time to complete. But as every patient is different, treatment is necessarily empirical, guided by close clinical observation. The authors describe examples of patients illustrating the relevant points.

    Branko Braam, Kailash Jindal, Evert J. Dorhout Mees
    Hypertension and Cardiovascular Aspects of Dialysis Treament - Clinical management of volume control
    Pabst, 192 pages. Paperback ISBN 978-3-89967-721-8

    Icon Special and general specialist literatureSpecial scientific titles & generally understandable specialist literature
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