The key sentences:
- Standard premedicant drugs such as benzodiapecines, barbiturates, opioids, and antihistamines do not cause problems in MH susceptible patients when administered in appropriate doses.
- Regional anaesthesia using either amide or ester local analgesics can safely be performed.
- General anaesthesia performed as total intravenous anaesthesia (TIVA) or balanced anaesthesia including nitrous oxide is safe, provided that care is taken to specially prepare the anaesthesia machine and to avoid anaesthetic trigger agents which are depolarizing muscle relaxants such as succinylcholine and all volatile anaesthetics (Halothane, Enflurane, Isoflurane, Desflurane, Sevoflurane). Dantrolene should be available at any time.
- The monitoring should include the standard variables ECG and blood pressure as well as endtidal CO2 and core body temperature. Additional arterial and/or central venous monitoring is recommended for MH susceptible patients, as dictated by the surgical procedure.